3-PHENYLUREIDO-AZEPIN-2-ONES AND BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS

摘要

2117367 9315059 PCTABS00024 The present invention relates to novel substituted hexahydroazepinones and tetrahydrobenzazepinones of formulae (I) and (II) wherein R1, Z1, Z2, Y1 and Y2 are as defined, and to novel intermediates used in the synthesis of such compounds. Such compounds are useful in the treatment and prevention of gastrointestinal disorders, pain and anxiety disorders.