发明名称 |
PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES |
摘要 |
The invention relates to 2-pyridone derivatives of general formula (I) in which Ar<1> is an optionally substituted phenyl ring; Ar<2> is an optinally substituted phenyl ring; R<1> is hydrogen or C1-4alkyl; R<2> is hydrogen or C1-4alkyl; R<3> is hydrogen or C1-4alkyl; R<4> and R<5> are the same or different and are each hydrogen, C1-4alkyl or C1-4alkylAr<1>, or R<4> and R<5> together form a group (CH=CH)2; and X is CH2 or NR<6> in which R<6> is hydrogen or C1-4alkyl or a salt thereof, and their use in therapy as gastric acid secretion inhibitors. |
申请公布号 |
WO9315056(A1) |
申请公布日期 |
1993.08.05 |
申请号 |
WO1993EP00175 |
申请日期 |
1993.01.26 |
申请人 |
SMITHKLINE BEECHAM INTERCREDIT B.V. |
发明人 |
IFE, ROBERT, JOHN;LEACH, COLIN, ANDREW;DHANAK, DASHYANT |
分类号 |
A61K31/44;A61K31/4418;A61K31/4425;A61K31/47;A61P1/04;C07D213/78;C07D215/54 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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