| 摘要 |
<p>17β-hydroxybenzoyl-4-aza-5α-androst-1-en-3-ones useful to treat baldness have formula (I), wherein R is selected from hydrogen, methyl and ethyl and R2 is phenyl substituted with one or more of: -OH, -OC¿1?-C4 alkyl, C1-C4 alkyl, -(CH2)mH, -(CH2)nCOOH, including protected -OH, where m is 1-4, n is 1-3, and providing C1-C4 alkyl is only present when one of the above oxygen containing radicals is present, wherein the dotted line represents a double bond which can be present, pharmaceutically acceptable salts and esters thereof, and a pharmaceutical formulation thereof.</p> |
