发明名称 |
Fluorinated cyclobutyl purines and pyrimidines. |
摘要 |
<p>Antiviral activity is exhibited by compounds having the formula <CHEM> or a pharmaceutically acceptable salt thereof wherein R1 is a purinyl, substituted purinyl, pyrimidinyl, or substituted pyrimidinyl, R6 is -OH, -CH2OH, -OPO3H2, -CH2-O-PO3H2, <CHEM> or <CHEM> and R7 is hydrogen, -PO3H2, or <CHEM> f</p> |
申请公布号 |
EP0554025(A2) |
申请公布日期 |
1993.08.04 |
申请号 |
EP19930300496 |
申请日期 |
1993.01.25 |
申请人 |
E.R. SQUIBB & SONS, INC. |
发明人 |
VITE, GREGORY D.;ZAHLER, ROBERT;SLUSARCHYK, WILLIAM A.;TINO, JOSEPH A.;SINGH, JANAK;KISSICK, THOMAS P. |
分类号 |
A61K31/505;A61K31/52;A61K31/522;A61P31/12;A61P31/22;C07C35/04;C07C35/48;C07C43/178;C07C43/315;C07C45/51;C07C49/753;C07C62/08;C07C69/757;C07C309/30;C07D239/47;C07D239/54;C07D239/553;C07D303/08;C07D303/18;C07D473/00;C07D473/16;C07D473/18;C07D473/32;C07D473/34;C07D473/40 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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