| 摘要 |
A support matrix suitable for the immobilization of biologically active materials comprises a core support made from a refractory inorganic oxide, glass or ceramic coated with a dialkylaminoalkyl ether of cellulose having groups of the formula RaRb (CH2)p, in which Ra and Rb are alkyl groups having 1 to 20 carbon atoms, and p is an integer from 2 to 10. The matrix can be used to immobilize biologically active material, e.g. proteinaceous material having an isoelectric point greater than 7.0 (e.g. enzymes, cofactors, antibodies or antigens). The matrix can be readily and repeatedly regenerated by washing with an aqueous base or salt solution. |
