STABILIZED ANTIULCER AGENT-CONTAINING PREPARATION

摘要

PURPOSE:To obtain a stabilized antiulcer agent-containing preparation by using both an amino acid and a buffering agent as stabilizers for a specific benzimidazole compound having an antiulcer activity but unstable against acids. CONSTITUTION:A benzimidazole compound having an antiulcer activity but unstable against acids [especially preferably 2-[(2-pyridyl) methylsulfinyl] benzimidazole compound] is compounded with the acid or alkali salt of an amino acid such as glycine or L-alanine and a buffering agent (preferably disodium hydrogenphosphate) as stabilizers to obtain a stabilized antiulcer agent-containing preparation. The amino acid and the buffering agent as the stabilizers are preferably compounded in amounts of 0.01-10 pts.wt. and 0.01-20 pts.wt., respectively, per pt.wt. of the benzimidazole compound.