PROCESS FOR THE PREPARATION OF DEXTROROTATORY 3-(3-PYRIDYL)-1H, 3H-PYRROLO(1,2-C)-7-THIAZOLECARBOXYLIC ACID

摘要

Process for the preparation of the acid of formula (I) by reaction of an ester of 2-chloroacrylic acid with an organic salt of cis or predominantly cis 3-formyl-2-(3-pyridyl)thiazolidine-4-carboxylic acid in the presence of an acid chloride and of triethylamine, and the ester of formula (VII) obtained is then saponified. ……