| 发明名称 |
Dual inhibitors of no synthase and cyclooxygenase, process for their preparation and therapeutical compositions containing them. |
| 摘要 |
The invention relates to compounds of the general formula AB, which may be a salt or an amide, wherein: A represents a cyclooxygenase inhibitor having an accessible acidic function and B represents the L-form of arginine analogues of the formula <IMAGE> wherein R1, R2 and R3 represent various substituents, process for the preparation of such compounds and pharmaceutical composition thereof. |
| 申请公布号 |
ZA9210080(B) |
申请公布日期 |
1993.08.02 |
| 申请号 |
ZA19920010080 |
申请日期 |
1992.12.29 |
| 申请人 |
SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.). |
发明人 |
PIERRE-ETIENNE CHABRIER DE LASSAUNIERE;PIERRE BRAQUET;COLETTE BROQUET;SERGE AUVIN |
| 分类号 |
A61K31/195;A61K31/196;A61K31/197;A61K31/198;A61K31/22;A61K31/415;A61K31/60;A61P3/06;A61P9/00;A61P9/10;A61P43/00;C07C57/30;C07C65/10;C07C69/157;C07C69/86;C07C229/58;C07C249/02;C07C251/08;C07C257/14;C07C257/22;C07C279/12;C07C279/14;C07C279/34;C07C279/36;C07C317/44;C07D209/28;C12N9/99 |
主分类号 |
A61K31/195 |
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