发明名称 |
METHOD OF TERMINAL STEAM STERILIZATION |
摘要 |
Disclosed is a method for terminal steam sterilization of a prefilled plastic syringe or a pre-filled plastic cartridge, said method comprising the steps of: maintaining a head space in the syringe or cartridge of less than about 10% volume; providing at least a 10% leeway for the plunger therein to slide in response to pressure differential; and sterilizing the syringe or cartridge at an autoclave pressure that is less than the internal pressure of the syringe or cartridge. Also disclosed is a method for terminal steam sterilization of a pre-filled glass syringe or pre-filled glass cartridge, said method comprising the steps of: maintaining a head space in the syringe or cartridge of less than about 10% volume; providing at least a 10% leeway for the plunger therein to slide in response to pressure differential; and sterilizing the glass syringe or glass cartridge at an autoclave pressure that is less than, equal to or greater than the internal pressure of the syringe or cartridge.
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申请公布号 |
CA2088331(A1) |
申请公布日期 |
1993.07.30 |
申请号 |
CA19932088331 |
申请日期 |
1993.01.28 |
申请人 |
STERLING WINTHROP INC. |
发明人 |
LIEBERT, RICHARD T.;BROWN, NEIL H.;PISTOLESE, JOHN R. |
分类号 |
A61L2/06;A61L2/00;A61L2/07;A61M5/178;(IPC1-7):A61L2/06 |
主分类号 |
A61L2/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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