1,5-Diphenyl-1H-1,2,4-triazole-3-carboxamide derivatives, process for preparation of the same, antifungal composition comprising the same.

摘要

A derivative of 1,5-diphenyl-1H-1,2,4-triazole-3-carboxamide represented by the following general formula (I), a process for the manufacture thereof, and an antimicrobial composition comprising it as an effective component <CHEM> wherein R<1> is a C1-C6 alkyl group, C3-C6 cycloalkyl group, C1-C5 fluoroalkyl group, (C1-C4 alkoxy)methyl group, or phenyl group, R<2> is a C1-C8 alkyl group, (C3-C6 cycloalkyl)methyl group, C2-C5 fluoroalkyl group, (C1-C4 alkoxy)(C1-C4 alkyl) group, phenyl group, phenylmethyl group, or phenylmethyl group substituted by a C1-C4 alkyl group or a halogen atom, X<1> is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 alkoxy group, or a halogen atom, X<2> is a hydrogen atom, a C1-C4 alkyl group, or a halogen atom, Y<1> is a hydrogen atom, a halogen atom, a C1-C4 alkyl group, a C1-C4 alkoxy group, a C1-C4 fluoroalkoxy group, a HO group, a HOOC group, or a (C1-C4 alkoxy) carbonyl group, Y<2> is a hydrogen atom, a C1-C4 alkyl group, or a halogen atom, Y<3> is a hydrogen atom or a halogen atom, and n is 1 or 2.