摘要 |
<p>PCT No. PCT/JP92/01658 Sec. 371 Date Jun. 24, 1994 Sec. 102(e) Date Jun. 24, 1994 PCT Filed Dec. 18, 1992 PCT Pub. No. WO93/13083 PCT Pub. Date Jul. 8, 1993Heterocyclic compounds of the formula: R1-Q-Z-X-A-M wherein R1 is lower alkyl, a heterocyclic group which may have suitable substituent(s), etc; Q is oxadiazolediyl, Z is bond or vinyl, X is bond, a group of the formula: <IMAGE> (in which R4 is hydrogen or lower alkyl), a group of the formula: <IMAGE> (in which R8 is hydroxy or protected hydroxy), etc; A is bond, lower alkylene or lower alkynylene and M is a heterocyclic group containing at least one nitrogen atom which may have one substituent selected from the group consisting of lower alkyl, an imino protective group and ar(lower)alkyl which may have suitable substituent(s), and a pharmaceutically acceptable salt thereof which are useful as a medicament.</p> |