| 发明名称 |
TRK TYROSINE KINASE RECEPTOR IS THE PHYSIOLOGICAL RECEPTOR FOR NERVE GROWTH FACTOR |
| 摘要 |
The present invention relates to a complex comprising nerve growth factor (NGF) and trk-proto-oncogene protein. The present invention also relates to methods for detecting the presence of NGF and trk-proto-oncogene receptor. The present invention further relates to methods that may be used in diagnostics and therapeutics for neurodegenerative diseases such as Alzheimer's and Huntington's by detecting NGF-trk receptor pairs.
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| 申请公布号 |
US5231001(A) |
申请公布日期 |
1993.07.27 |
| 申请号 |
US19910668298 |
申请日期 |
1991.03.14 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
KAPLAN, DAVID;MARTIN-ZANCA, DIONISIO;PARADA, LUIS F. |
| 分类号 |
C07K14/52;A61K38/00;C07K14/00;C07K14/48;C07K14/705;C07K14/71;C07K14/715;C07K16/00;C07K19/00;C12Q1/02;C12R1/91;G01N33/53;G01N33/564;G01N33/566;G01N33/574;G01N33/68 |
主分类号 |
C07K14/52 |
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