| 发明名称 |
Azacyclic carboxylic acid derivatives and their preparation and use |
| 摘要 |
Novel O-alkylated oximes of the general formula I <IMAGE> (I) or <IMAGE> wherein R1 and R2 are optionally substituted aromatic or heteroaromatic rings, R3 is hydrogen or lower alkyl, R4 is a nitrogen containing, substituted ring or an amino group carrying a substituted ring, and n and m independently are 0, 1 or 2, are potent inhibitors of GABA reuptake from the synaptic cleft.
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| 申请公布号 |
US5231106(A) |
申请公布日期 |
1993.07.27 |
| 申请号 |
US19910804902 |
申请日期 |
1991.12.06 |
| 申请人 |
NOVO NORDISK A/S |
发明人 |
KNUTSEN, LARS J. S.;ANDERSEN, KNUD E.;JORGENSEN, ANKER S.;SONNEWALD, URSULA |
| 分类号 |
A61K31/40;A61K31/44;C07D207/10;C07D401/12 |
主分类号 |
A61K31/40 |
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