CELL PROLIFERATION PROMOTING AGENT AND PROMOTING METHOD

摘要

PURPOSE:To provide the subject promoting agent composed of a oxazopyrroloquinoline compound or its ester and effective for promoting the proliferation of animal cell to increase the production efficiency of valuable products originated from the cell. CONSTITUTION:The objective promoting agent is composed of an oxazopyrroloquinoline compound and/or its ester expressed by formula [R is same as the R' of an alpha-amino acid of the formula R'-CH2(NH2)COOH; R<2> to R<3> are H, alkyl, alkenyl or benzyl]. The compound of formula is produced preferably by reacting a PQQ compound with various alpha-amino acids (e.g. glycine and valine) and methylamine, etc., in the presence of oxygen.