| 摘要 |
The invention relates to indoles of general formula (I), wherein R0 represents a hydrogen atom or a C1-3 alkyl group; R1 represents a group R4CONH-, R4R5NSO2-, R4SO2NH- or R4R5NCO- (where R4 represents a hydrogen atom or a C1-6 alkyl group, provided that R4 does not represent a hydrogen atom when R1 represents R4SO2NH-, and R5 represents a hydrogen atom or a C1-6 alkyl, C3-7 cycloalkyl, phenyl or phen(C1-3)alkyl group in which the phenyl ring is optionally substituted by a halogen atom or a C1-4 alkoxy, hydroxy or C1-3 alkyl group); R2 represents a hydrogen atom or a C1-3 alkyl, C3-6 alkenyl, phenyl or phen(C1-3)alkyl group; R3 represents a hydrogen atom, a C1-3 alkyl group or a group -CO2R6, -COR6, -COCO2R6 or -CONHR6 where R6 represents a hydrogen atom or a C1-4 alkyl, C3-7 cycloalkyl, C3-6 alkenyl, aryl or ar(C1-4)alkyl group in which the aryl group may be unsubstituted or substituted by a halogen atom or a C1-4 alkoxy, C1-4 alkyl or hydroxy group (provided that when R3 represents -CO2R6, R6 is other than hydrogen); n represents zero or an integer from 1 to 5; and pharmaceutically acceptable salts thereof. |
