| 摘要 |
<p>Compounds of general formula (I), wherein R1 represents a phenyl, C¿3-7?cycloalkyl, bridged C7-11cycloalkyl or C1-6alkyl group which alkyl group may be substituted by a hydroxy, phenyl, C1-6alkoxycarbonyl, C3-7cycloalkyl or bridged C7-11cycloalkyl group or R?1¿ represents the group XYR4 wherein X is a C¿1-3? straight or branched alkylene chain, Y is C=O, C(OR?5)¿2 or C(SR5)2 and R4 is a C¿1-6?alkyl, optionally substituted phenyl, C3-7cycloalkyl or bridged C7-11cycloalkyl. R?2¿ represents a substituted or unsubstituted phenyl (wherein the substituents may be 1 or 2 of halo, C¿1-4?alkyl, nitro, cyano, trifluoromethyl, trifluoromethoxy C1-4alkylthio or (CH2)nR?6¿ wherein R6 is hydroxy, C¿1-4?alkoxy, CO2R?7 or NR8R9. R3¿ represents phenyl optionally substituted by one or two halogen atoms; R7 represents hydrogen or a C¿1-4?alkyl group; R?8 and R9¿ independently represent hydrogen or a C¿1-4?alkyl group. R?10¿ represents hydrogen or a halogen atom; m is 0, 1 or 2; n is 0 or 1; are antagonists of gastrin and CCK-B receptors.</p> |
