发明名称 PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER DERIVATIVE-BOUND ANTHRACYCLINE GLYCOSIDES AND A METHOD FOR THEIR PREPARATION
摘要 <p>A lyophilized composition comprising (a) a conjugate comprising an N-alkyl methacrylamide-based copolymer and an anthracycline glycoside linked through a peptide spacer to the copolymer and (b) a cosolubilizing agent may optionally also contain (c) a filler. Also optionally, a targeting moiety may be linked to the copolymer of the conjugate via a peptide spacer. An injectable solution of the conjugate is obtained by reconstitution of the lyophilized composition.</p>
申请公布号 WO1993013804(A1) 申请公布日期 1993.07.22
申请号 EP1992002968 申请日期 1992.12.21
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