发明名称 1,5-BENZODIAZEPINE DERIVATIVES
摘要 Compounds of general formula (I) (see Formula I) wherein R1 represents a phenyl, C3-7cycloalkyl, C7-11 bridgedcycloalkyl or C1-6alkyl group which alkyl group may be substituted by a hydroxy; phenyl, C1-6alkoxycarbonyl; C3-7cycloalkyl, or C7-11 bridgedcycloalkyl group; R2 represents a substituted or unsubtituted phenyl group (wherein the substitutents may be 1 or 2 of halo, C1-4alkyl, nitro, cyano, trifluoromethyl, trifluoromethox y, C1-4alkylthio or (CH2)n R4 wherein R4 is hydroxy, C1-4alkoxy, CO2R5 or NR6R7. R3 is phenyl optionally substituted by one or two halogen atoms; R5 represents hydrogen or a C1-4alkyl group; R6 and R7 independently represent hydrogen or a C1-4alkyl group. R8 represents hydrogen or a halogen atom; m is zero, 1 or 2; n is zero or 1; are antagonists of gastrin and CCK-B receptors
申请公布号 CA2087672(A1) 申请公布日期 1993.07.22
申请号 CA19932087672 申请日期 1993.01.20
申请人 GLAXO SPA 发明人 FINCH, HARRY;TRIST, DAVID;TARZIA, GIORGIO;FERIANI, ALDO
分类号 A61K31/55;A61K31/551;A61P1/00;A61P1/04;A61P25/00;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P43/00;C07D243/12;(IPC1-7):C07D243/12 主分类号 A61K31/55
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