| 摘要 |
The invention concerns a 1,2-dihydro-3_H-indazol-3-one derivative of formula I <IMAGE> I wherein Ra is hydrogen, halogeno, hydroxy, cyano, trifluoromethyl, (1-6C)alkyl or (1-6C)alkoxy; Rb is hydrogen or (1-6C)alkyl; Rc is hydrogen, (1-8C)alkyl or (3-8C)alkenyl; and Y is (1-8C)alkyl, (3-8C)alkenyl or (3-8C)alkynyl, or Y is a group of the formula -A-Q in which A is (1-6C)alkylene or (3-6C)alkenylene, and Q is phenyl or naphthyl, which may optionally bear one or two substituents; or a pharmaceutically-acceptable salt thereof; or a 1-(1-4C)alkoxycarbonyl derivative thereof. The invention also concerns processes for the manufacture of an indazol-3-one of the formula I and pharmaceutical compositions containing said indazol-3-one. Also included in the invention is a method of treating various inflammatory or allergic diseases using an indazol-3-one of the formula I.
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