| 摘要 |
<p>A method for diagnostic and prognostic monitoring of genotoxic changes in tissue arising from oxidative modifications of the genus consisting of the DNA nucleotide bases containing purine or pyrimidine or structurally or metabolically similar surrogates by analyzing the altered bases or surrogates and comparing those results to baseline levels. [See In re Harmisch, 206 USPQ 300 (1980)]. This method is directed towards diagnosing or predicting the occurrence of neoplasia (cancerous growth), assaying the impact of genotoxic effects brought about by exposure to environmental chemicals, and tracking the effects of such modifications over time in response to oxidative repressing agents.</p> |
