发明名称 |
PHARMACEUTICAL COMPOSITIONS |
摘要 |
PHARMACEUTICAL COMPOSITIONS Complexes of B-cyclodextrin with various salts of ibuprofen are described in which the molar ratios of ibuprofen to B-cyclodextrin are within the range of from 1:0.20 to 1:0.75. The preferred salt of ibuprofen is the sodium salt. The complexes have enhanced taste profile and bioavailability. Also disclosed are methods for preparing the complexes and also pharmaceutical compositions thereof. |
申请公布号 |
CA1320192(C) |
申请公布日期 |
1993.07.13 |
申请号 |
CA19890600940 |
申请日期 |
1989.05.29 |
申请人 |
RECKITT & COLMAN PRODUCTS LIMITED |
发明人 |
HUNTER, CHRISTOPHER;YAU, DAVID |
分类号 |
A61K9/18;A61K31/19;A61K47/40;A61K47/48;C07C57/30;C07C229/08;C07C229/26;C07C279/14;C08B37/16 |
主分类号 |
A61K9/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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