发明名称 |
Redox active compounds and their use |
摘要 |
The use of polycyclic aza-heterocyclic fused quinone derivatives of formula (I) and/or (II) or their salts is claimed for the preparation of detection reagents for analyses. Also claimed are: (1) reagents for the determination of an analyte in a sample which comprise at least one compound (I) and/or (II); and (2) reagent kits containing the reagents and other test components. R1,R2 = H, halogen or organic residue; X = O, S, CH(Acc) or N(Acc); Acc = electron-withdrawing group; Ph' = optionally substituted phenyl ring; n = 0-4; Ar = fused poly-aza, polycyclic ring system of formula (Ar1)-(Ar8); Y,Y' = N or CR6; R3-R6,R'3-R'5 = H, halogen or organic residue; Z = NR, O or S; R = H or organic residue; R' = alkyl or aryl (both optionally substituted); m = 0-1, with the proviso that if m = 1 in (Ar1), (Ar3), (Ar5) and (Ar7), then the N bonded to R' has a positive charge and a counter-ion is present; p = 0 if m = 1, or p = 1 if m = 0. Compounds (I) and (II) containing at least one hydrophilic group are new, with the exception of indanthrene monosulphonic acid, indanthrene disulphonic acid and their sodium and potassium salts. |
申请公布号 |
EP0831327(A1) |
申请公布日期 |
1998.03.25 |
申请号 |
EP19970116653 |
申请日期 |
1997.09.24 |
申请人 |
ROCHE DIAGNOSTICS GMBH |
发明人 |
HEINDL, DIETER, DR.;HERRMANN, RUPERT, DR.;HOENES, JOACHIM, DR.;JOSEL, HANS-PETER, DR.;JUNIUS-COMER, MARTINA, DR.;MERDES, HARTMUT, DR.;SCHMIDT, AXEL, DR.;SELBERTINGER, ERNST, DR. |
分类号 |
C07D241/38;C07D241/46;C07D401/14;C07D471/04;C07D487/04;C07D491/048;C07D495/04;C12Q1/26;G01N31/22;G01N33/52 |
主分类号 |
C07D241/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|