发明名称 |
Dye-labeled protein conjugate and method for preparing the same |
摘要 |
<p>The present invention provides a dye-labeled protein conjugate in which a protein conjugate is labeled with a large number of dye molecules. In the dye-labeled protein conjugate, a protein conjugate that includes a protein and an antibody bound thereto via a disulfide bond is labeled with a cyanine dye represented by the formula (1) given below. <CHEM> where R1 and R2 denote hydrogen or an alkyl group, X denotes a halogen, M denotes hydrogen or an alkali metal, and n represents an integer in a range of 1 to 4.</p> |
申请公布号 |
EP0957364(A2) |
申请公布日期 |
1999.11.17 |
申请号 |
EP19990108597 |
申请日期 |
1999.05.07 |
申请人 |
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. |
发明人 |
SHIGETOU, NOBUYUKI;MIYAZAKI, JINSEI;NAKAYAMA, HIROSHI |
分类号 |
G01N21/64;C07D403/14;C07K16/00;C09B23/00;G01N33/531;G01N33/532;(IPC1-7):G01N33/532 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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