PYRIDOBENZOTHIAZINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME

摘要

Pyridobenzothiazine derivatives having tachykinin antagonism, in particular, substance P receptor antagonism. Namely, pyridobenzothiazine derivatives represented by general formula (1) and salts thereof and medicinal compositions containing these compounds or pharmaceutically useful salts thereof, wherein R<1>, R<2> and R<3> are the same or different and each represents hydrogen or C1-6 alkyl; the ring A is a homocycle or a heterocycle optionally having 1 to 3 substituents selected independently (wherein 2 substituents adjacent to each other may be bonded together to form a ring); the ring B is a benzene ring optionally having 1 to 5 substituents (wherein 2 substituents adjacent to each other may be bonded together to form a ring); and the ring C is a benzene ring optionally having 1 to 3 substituents (wherein 2 substituents adjacent to each other may be bonded together to form a ring).