摘要 |
<p>There is provided a process for the preparation of substituted and unsubstituted-2,3-pyridinedicarboxylate compounds by reacting a dialkyl dichloromaleate with a dialkylamine to form an enamine intermediate and reacting said intermediate with an appropriately substituted alpha , beta -unsaturated aldehyde or ketone and an ammonia source, as shown in Flow Diagam I: <CHEM> o</p> |