发明名称 Antiallergic, antiinflammatory and anti-PAF pyridazine compounds.
摘要 <p>Novel compound represented by the formula: &lt;CHEM&gt; wherein X stands for a methine group (i.e. the group -CH=) or a nitrogen atom; R&lt;1&gt; stands for a hydrogen atom, an optionally substituted lower alkyl group or a halogen atom; R&lt;2&gt; and R&lt;3&gt; respectively stand for a hydrogen atom or an optionally substituted lower alkyl group, or, taken together, may form a 5- to 7-membered ring combined with the adjacent -C=C-; R&lt;4&gt; and R&lt;5&gt; respectively stands for a hydrogen atom or an optionally substituted lower alkyl group or, taken together, form a 3- to 7-membered homo- or hetero-cyclic ring combined with the adjacent carbon atom; A stands for an optionally substituted amino group; m and n denote 1 to 4, respectively, or salts thereof which has an antiallergic, antiinflammatory and anti-PAF activity and is useful as an antiasthmatic agent.</p>
申请公布号 EP0548923(A2) 申请公布日期 1993.06.30
申请号 EP19920121818 申请日期 1992.12.22
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 MIYAKE, AKIO;KAWANO, YASUHIKO;ASHIDA, YASUKO
分类号 C07D487/04 主分类号 C07D487/04
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