| 发明名称 |
Endothelin antagonists. |
| 摘要 |
<p>An endothelin antagonistic peptide represented by the formula (I): <IMAGE> wherein Xaa1 represents Asp, Asn or Glu; Xaa2 represents Lys or Arg; Xaa3 represents Glu, Gln or Asp; Xaa4 represents Tyr or Phe; Xaa5 represents Asp or Gly; and Xaa6 represents Trp or Phe; as well as a pharmaceutical preparation comprising the peptide. <IMAGE></p> |
| 申请公布号 |
EP0548441(A1) |
申请公布日期 |
1993.06.30 |
| 申请号 |
EP19910810997 |
申请日期 |
1991.12.23 |
| 申请人 |
JAPAT LTD |
发明人 |
URADE, YOSHIHIRO;TAKAI, MICHIHIRO;WATAKABE, TADASHI;YAMAMURA, TAKAKI;OKADA,TOSHIKAZU;KARAKI, HIDEAKI |
| 分类号 |
A61K38/00;C07K14/575;(IPC1-7):C07K15/00;A61K37/24 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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