发明名称 |
HETEROCYCLICALLY SUBSTITUTED CYCLOALKANO(B)-INDOLESULPHONAMIDES |
摘要 |
Heterocyclically substituted cycloalkano[b]-indolesulphonamides can be prepared by reaction of appropriate N-unsubstituted indoles with acrylonitrile, followed by hydrolysis, esterification or amidation, or by reaction of heterocyclically substituted hydrazines with cycloalkanones or by subsequent introduction of the heterocyclic group into appropriate indole derivatives. The heterocyclically substituted cycloalkano[b]-indolesulphonamides can be employed for the treatment of thromboembolic disorders, ischaemias, arteriosclerosis, asthma, allergies and for the prophylaxis of myocardial infarcts.
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申请公布号 |
US5223517(A) |
申请公布日期 |
1993.06.29 |
申请号 |
US19910749018 |
申请日期 |
1991.08.23 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
MUELLER, ULRICH E.;NIEWOEHNER, ULRICH;PERZBORN, ELISABETH;BISCHOFF, ERWIN;DELLWEG, HANS-GEORG |
分类号 |
A61K31/40;A61K31/403;A61K31/44;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/635;A61P7/02;A61P9/08;A61P9/10;A61P11/00;A61P37/08;C07D209/86;C07D209/88;C07D213/24;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/06;C07D405/06;C07D409/06;C07D417/06 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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