发明名称 |
Bordetella pertussis variants |
摘要 |
A Bordetella pertussis variant which produces a pertussis toxin mutant protein partially devoid of subunits. When the variants of the present invention are cultured, a pertussis toxin mutant protein partially devoid of subunits, particularly at least subunit S1, can be harvested from the culture. The thus-obtained pertussis toxin mutant protein partially devoid of subunits can be applied to the preparation of a pertussis vaccine by a conventional method.
|
申请公布号 |
US5223255(A) |
申请公布日期 |
1993.06.29 |
申请号 |
US19910774637 |
申请日期 |
1991.10.11 |
申请人 |
TEIJIN LIMITED;NATIONAL INSTITUTE OF HEALTH |
发明人 |
SATO, YUJI;SATO, HIROKO;YOSHIDA, IWAO;IMAIZUMI, ATSUSHI |
分类号 |
A61K39/00;C07K14/235;C12P21/04 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|