摘要 |
A method for preparing d,1-5-methyltetrahydrofolic acid and the salts thereof of the formula: <IMAGE> (I) wherein X is hydrogen, an alkaline metal or alkaline earth metal; by reduction of folic acid with sodium borohydride followed by the methylation of the tetrahydrofolic acid thus obtained with aqueous solutions of formaldehye and sodium borohydride in an inert atmosphere.
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