发明名称 NOUVEAUX 19-NOR STEROUIDES AYANT EN POSITION 11BETA UNE CHAINE THIOCARBONEE, LEUR PROCEDE DE PREPARATION ET LES INTERMEDIAIRES ET LEUR APPLICATION A TITRE DE MEDICAMENTS.
摘要 Compounds of formula (I), wherein R17 and R'17 are such that: either R17 and R'17 together form ketone, hydrazono, oxime or methylene, or R17 is hydroxyl, hydroxymethyl or acyloxy and R'17 is hydrogen, alkyl or optionally substitued alkenyl or alkynyl; R3 is hydrogen or alkyl; R16 is hydrogen, halogen or alkyl; m is 0, 1 or 2; X, Y and Z are such that: X is methylene, arylene or arylenoxy bonded to the steroid by a carbon atom; Y is a saturated or unsaturated straight or branched aliphatic chain which is optionally interrupted by oxygen; and Z is aryl, arylalkyl or straight or branched alkyl; addition salts thereof, a preparation method therefor, medicinal uses thereof, compositions containing said compounds, and resulting novel intermediates.
申请公布号 FR2685332(A1) 申请公布日期 1993.06.25
申请号 FR19910015856 申请日期 1991.12.20
申请人 ROUSSEL UCLAF 发明人 CLAUSSNER ANDRE;NIQUE FRANCOIS;TEUTSCH GEORGES;VAN DE VELDE PATRICK
分类号 A61K31/56;A61K31/565;A61K31/57;A61K31/575;A61K31/58;A61K31/585;A61P5/30;A61P15/00;A61P35/00;C07J3/00;C07J5/00;C07J7/00;C07J9/00;C07J11/00;C07J21/00;C07J31/00;C07J41/00;C07J43/00;(IPC1-7):C07J31/00;C07J1/00 主分类号 A61K31/56
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