发明名称 NUCLEASE STABLE AND BINDING COMPETENT OLIGOMERS AND METHODS FOR THEIR USE
摘要 Oligomers are disclosed which have modified internucleotide linkages and can form triplex and duplex structures by binding to complementary nucleic acid sequences. The oligomers of the invention may be incorporated into pharmaceutically acceptable carriers and may be constructed to have any desired sequence. Compositions of the invention can be used as pharmaceutical agents to treat various diseases such as viruses and can be used for diagnostic purposes in order to detect viruses or disease conditions.
申请公布号 WO9312135(A1) 申请公布日期 1993.06.24
申请号 WO1992US10793 申请日期 1992.12.11
申请人 GILEAD SCIENCES, INC. 发明人 SWAMINATHAN, SUNDARAMOORTHI;JONES, ROBERT, J.;MATTEUCCI, MARK;MUNGER, JOHN;PUDLO, JEFF
分类号 C07H21/00;C12Q1/68 主分类号 C07H21/00
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