7'-AMINO-NAPHTHAZARIN ANTIBIOTIC DERIVATIVES

摘要

New naphthazarin derivatives of formula (I) obtained by introducing in the 7' position of Purpuromycin or gamma -Rubromycin an amino or a monosubstituted amino group. The compounds of the invention show antibiotic activity against Gram positive and Gram negative microorganisms, fungi and protozoa and are suitable for the treatment of vaginal infections. Compounds of formula (IV) and (V) are also claimed.