发明名称 |
22-OXACHOLECALCIFEROL DERIVATIVE AND PRODUCTION THEREOF |
摘要 |
A 22-oxacholecalciferol derivative represented by general formula (I) and a process for producing the same efficiently by reducing the amount of by-products, wherein R1 represents hydrogen or hydroxy, and R2 and R3 may be the same or different from each other and represent each C1-C5 alkyl. This compound has potent activities of inducing differentiation and suppressing proliferation and is promising as antitumor agent, antirheumatic, psoriasis curative and remedy for hyperparathyroidism. |
申请公布号 |
WO9312083(A1) |
申请公布日期 |
1993.06.24 |
申请号 |
WO1992JP01662 |
申请日期 |
1992.12.18 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
KATO, MASAHIRO;MIKAMI, TETSUHIRO;OCHI, KIYOSHIGE;WATANABE, HIROYOSHI;KUBODERA, NOBORU |
分类号 |
A61K31/59;A61P3/02;A61P5/12;A61P29/00;A61P35/00;C07C401/00;C07J7/00;C07J51/00;C07J71/00 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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