发明名称 POLYETHYLENOXIDE MIT EINER SACCHARIDGRUPPE AN EINEM ENDE UND EINER ANDEREN FUNKTIONELLEN GRUPPE AM ANDEREM ENDE SOWIE VERFAHREN ZU DEREN HERSTELLUNG
摘要 This invention provides a heterotelechelic oligomer or polymer which is represented by the following formula: <CHEM> wherein A denotes a sugar residue, L denotes a linkage group represented by the following formula <CHEM> or &lparstr& CH2 &rparstr& 4 wherein R<1> and R<2> independently denote lower alkyl, aralkyl or aryl, X denotes a single bond or -CH2CH2-, Z denotes a group forming an unsaturated ester or ether, or a functional group such as halogen which binds to -CH2CH2-, n denotes an integer of 5 - 10,000, and m denotes an integer of 0 or 2 - 10,000. This invention also provides a process to produce the above oligomer or polymer, and further a high molecular-micelle with use of a polyethylene oxide-polyester block polymer which has a sugar residue at its terminal. Said oligomer or polymer is expected to exhibit excellent bioavailability, and is also expected to be utilized in the field such as carriers for drug delivery or diagnostic reagents.
申请公布号 AT226966(T) 申请公布日期 2002.11.15
申请号 AT19960909364T 申请日期 1996.04.12
申请人 KATAOKA, KAZUNORI 发明人 KATAOKA, KAZUNORI;NAGASAKI, YUKIO;KATO, MASAO;OKANO, TERUO;NAKAMURA, TERUO
分类号 C08G65/32;A61K47/48;C08G63/664;C08G65/26;C08G65/329;C08L71/02;(IPC1-7):C08G65/32 主分类号 C08G65/32
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