| 发明名称 |
Inhibitors of farnesyl protein transferase. |
| 摘要 |
<p>The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.</p> |
| 申请公布号 |
EP0547669(A2) |
申请公布日期 |
1993.06.23 |
| 申请号 |
EP19920203806 |
申请日期 |
1992.12.08 |
| 申请人 |
MERCK & CO. INC. |
发明人 |
SINGH, SHEO BUX |
| 分类号 |
A61P35/00;A61K31/19;A61K31/23;A61P43/00;C07C57/13;C07C57/155;C07C69/593;C12N9/99 |
主分类号 |
A61P35/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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