发明名称 RENIN INHIBITING PEPTIDES HAVING AN (ALPHA)-HETEROATOM AMINO ACID AT THE P3 POSITION
摘要 The invention concerns novel renin-inhibitory compounds which are useful for treating renin-associated hypertension, congestive heart failure, hyperaldosteronism, glaucoma, and diseases caused by retroviruses including HTLV-I -II, and -III. Processes for preparing the compounds, novel intermediates useful in the preparation thereof, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, congestive heart failure, or hyperaldosteronism.
申请公布号 US5221667(A) 申请公布日期 1993.06.22
申请号 US19900468391 申请日期 1990.01.22
申请人 WARNER-LAMBERT COMPANY 发明人 KALTENBRONN, JAMES S.;REPINE, JOSEPH T.
分类号 A61K38/00;C07K5/02;C07K5/06;C07K5/065;C07K5/083 主分类号 A61K38/00
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