发明名称 Activated polymers and conjugates thereof
摘要 Macromolecular species such as enzymes, proteins, drugs, and solid supports which contain reactive carbonyl groups or groups which are readily converted to reactive carbonyl groups are modified by reaction with a compound of the formula <IMAGE> in which R1 is H, C1-C20 alkyl, phenyl, (C1-C10 alkyl)-substituted phenyl, or phenyl-substituted C1-C10 alkyl; R2 is C2-C5 alkylene or (C1-C4 alkoxy)-substituted C2-C5 alkylene; R3 is <IMAGE> <IMAGE> R4 is H or C1-C4 alkyl; n is at least 5; and m is zero or 1.
申请公布号 US5221771(A) 申请公布日期 1993.06.22
申请号 US19920914688 申请日期 1992.07.15
申请人 XOMA CORPORATION 发明人 REARDAN, DAYTON T.;GOFF, DANE A.
分类号 C07C229/60;C07C237/32;C07C271/28;C08G65/322;C08G65/333;C08G65/338;C12N11/08 主分类号 C07C229/60
代理机构 代理人
主权项
地址