PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE .ALPHA.-HYDROXYCARBOXYLIC ACIDS

摘要

Process for the preparation of optically active .alpha.-hydroxycarboxylic acids A b s t r a c t The invention relates to a process for the preparation of optically active .alpha.-hydroxycarboxylic acids characterised in that carbamates are first reacted in the presence of a selective base and of a chelateforming diamine to give a carbanion complex compound, this is than dia- or enantioselectively deprotonated, then substituted with CO2 and, as a final step, the heterocyclic protective group is eliminated. Le A 28 839 A- Foreign Countries