BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY

摘要

T1135Y BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY Compounds of formula (I), and salts and prodrugs thereof (I) wherein: R1 is H, certain optionally substituted C1-6alkyl, or C3-7cyclocalkyl; R2 represents a group wherein X is O, S or NR8 where R3 is H or C1-4alkyl; R3 is C1-6alkyl, halo or NR6R7; R4 is C1-7alkyl, C3-7cycloalkyl, C4-7cycloalkylalkyl or optionally substituted aryl; n is O, 1, 2 or 3; are CCK and/or gastrin receptor antagonists. They and compositions thereof are useful in therapy.