发明名称 |
The synthesis of peptide amides by means of a solid phase method using acid-labele anchoring groups |
摘要 |
Novel compounds of the formula …<IMAGE>… in which R<1> denotes (C1-C8)-alkyl or optionally substituted (C6-C14)-aryl, R<2> denotes hydrogen or an amino acid radical which is protected by an amino protective group which can be removed by a weak acid or base, R<3> denotes hydrogen or (C1-C4)-alkyl and Y<1>-Y<9> denote identical or different radicals of hydrogen, (C1-C4)-alkyl, (C1-C4)-alkoxy or -O-(CH2)n-COOH, (with n = 1 to 6), where one of these radicals is -O-(CH2)n-COOH. …<??>A process for their preparation and the synthesis of peptide amides by the solid phase method using these novel compounds (spacers) are described. |
申请公布号 |
PH27398(A) |
申请公布日期 |
1993.06.21 |
申请号 |
PH19530000367 |
申请日期 |
1988.06.06 |
申请人 |
HOECHST AKTIENGESELLSCHAFT. |
发明人 |
GERHARD BREIPHOL;JOCHEN KNOLLE;WERNER STUBER |
分类号 |
C07C69/675;C07C51/00;C07C59/125;C07C59/68;C07C67/00;C07C213/00;C07C213/02;C07C217/58;C07C239/00;C07C271/08;C07C271/34;C07K1/04;C07K1/08;C07K1/113;C07K7/16;C07K14/575 |
主分类号 |
C07C69/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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