| 摘要 |
For example, a method of inhibiting the coagulation of composite particles comprising lead (or leader) particles and, adhering thereto, a drug, characterized in that a surfactant, or fatty acid derivative or lipid derivative of at least one substance selected from among sugars, peptides, nucleic acids and water-soluble polymers is contained in the lead particles. Further, there is provided, for example, a process for producing composite particles composed of lead particles having a nucleic acid as drug or a drug adhering thereto, which process comprises the step of causing a nucleic acid as drug or a drug and an adhesion-competitive agent to be contained through dispersion or dissolution in a liquid wherein lead particles containing a surfactant, or fatty acid derivative or lipid derivative of at least one substance selected from among sugars, peptides, nucleic acids and water-soluble polymers are dispersed so that not only the nucleic acid as drug or the drug but also the adhesion- competitive agent adheres to the lead particles.
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