发明名称 GAS AND OXYGEN CARRYING LIPID VESICLES
摘要 The present invention relates to the production of lipid vesicles having a moderately volatile material such as a perfluorocarbon or a silicone oil encapsulated therein. In another aspect, lipid vesicles having a gas-filled center or core are made. The lipid vesicles having gas-filled central core are made by dehydrating vesicles having the moderately volatile liquid encapsulated in the central core. This drives off the water first, allowing the moderately volatile liquid to stabilize the vesicle structure as it dries, finally forming a central void which can refract light. The preferred vesicles of the invention are paucilamellar vesicles.
申请公布号 US5219538(A) 申请公布日期 1993.06.15
申请号 US19910662850 申请日期 1991.03.01
申请人 MICRO-PAK, INC. 发明人 HENDERSON, SHERYL L.;WALLACH, DONALD F. H.;MATHUR, RAJIV
分类号 A61K8/14;A61K8/70;A61K9/00;A61K9/127;A61K49/22;A61Q19/00;B01J13/02;B01J13/20;C08K9/04;C08L101/00;C11D17/00 主分类号 A61K8/14
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