Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same

摘要

The present invention relates to novel optically active isoxazole derivatives represented by general formula: <IMAGE> [XI] which are useful as intermediates for synthesis of prostaglandin and a process for producing the same as well as novel aldehyde compounds represented by general formula: <IMAGE> [IX] which are intermediates for preparing the compounds [XI] described above and a process for preparation thereof. In the compounds shown by these formulae, R1 represents an alkyl group or a cycloalkyl group which may have an alkoxy group or a group shown by -Ra-A-B (wherein Ra is an alkyl group; A is a hetero atom or an single bond; and B is an aromatic or hetero ring which may have a substituent(s)); and R2 and R3, which may be the same or different, each represents an aralkyl group, a silyl group or an acyl group.