ROTAVIRUS NUCLEOCAPSID PROTEIN WITH OR WITHOUT BINDING PEPTIDES AS IMMUNOLOGIC CARRIERS FOR MACROMOLECULES

摘要

New immunological carrier complexes are provided utilizing the VP6 polypeptide from rotavirus as the carrier molecule. Also provided are methods of binding epitope-bearing molecules (e.g., haptens) to the VP6 carrier molecule through binding peptides. The VP6 carrier can be a VP6 monomer, oligomer, or a particle comprised of VP6 oligomers.