发明名称 |
NITROSYLATION OF PROTEIN SH GROUPS AND AMINO ACID RESIDUES AS A THERAPEUTIC MODALITY |
摘要 |
The invention relates to the therapeutic use of S-nitroso-lipoprotein for regulating protein function, cellular metabolism and effecting vasodilation, platelet inhibition, relaxation of non-vascular smooth muscle and to deliver nitric oxide in its most bioactive form in order to achieve the effects described above. |
申请公布号 |
AU3071592(A) |
申请公布日期 |
1993.06.15 |
申请号 |
AU19920030715 |
申请日期 |
1992.11.13 |
申请人 |
BRIGHAM AND WOMEN'S HOSPITAL |
发明人 |
JONATHAN STAMLER;JOSEPH LOSCALZO;DANIEL SIMON;DAVID SINGEL |
分类号 |
A61K35/14;A61K38/00;A61K38/02;A61K38/16;A61K38/38;A61K38/42;A61K38/46;A61K38/49;A61K39/395;A61P9/00;C07K1/06;C07K1/107;C07K14/00;C07K14/315;C07K14/47;C07K14/76;C07K14/765;C07K14/805;C07K16/00;C07K16/18;C12N9/00;C12N9/48;C12N9/64;C12N9/70;C12N9/72 |
主分类号 |
A61K35/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|