Chimeras of parainfluenza virus type 3 protein F and HN as vaccines.

摘要

The invention relates to recombinant PIV3 fusion proteins or immunogenic derivatives thereof comprising a portion of the F protein of PIV3 fused to a portion of the HN protein of PIV3, methods of constructing and expressing these, intermediates for use therein and recombinant proteins obtained from the intermediates. Recombinant proteins of the invention have potential utility in the prevention of PIV3 infection.