摘要 |
<p>This invention relates to a method and apparatus that allows for the metabolic interaction of several cell types among separate, multiple compartments. Several chambers (21, 23, 25), each containing a different cell type, are connected to allow simultaneous exposure to added chemicals or exchange of metabolites among the various cellular compartments. The flow among the compartments is controlled by a pump or pumps (29); the rate(s) of flow may be adjusted to model physiologic flow rates. The device can therefore serve as a physiologic modeling system for the interaction of two or more cell or tissue types.</p> |