发明名称 |
MULTIMERIC FORMS OF MEMBERS OF THE STEROID/THYROID SUPERFAMILY OF RECEPTORS |
摘要 |
In accordance with the present invention, it has been discovered that various members of the steroid/thyroid superfamily of receptors can interact to form multimeric species comprising a complex of more than one receptor. Accordingly, the interaction of a first receptor species with a second receptor species modulates the ability of the first receptor species to trans-activate transcription of genes maintained under hormone expression control in the presence of the cognate ligand for said first receptor. |
申请公布号 |
WO9311235(A1) |
申请公布日期 |
1993.06.10 |
申请号 |
WO1992US10508 |
申请日期 |
1992.12.03 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
EVANS, RONALD, M.;KLIEWER, STEPHEN, A.;UMESONO, KAZUHIKO |
分类号 |
C12N15/09;A61K38/00;C07K14/705;C07K14/72;C07K19/00;C12N15/12;C12P21/02;C12R1/01;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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