Antibodies specific for RAR-gamma or a specific isoform of RAR-gamma.

摘要

The present invention discloses methods for preparing antibodies which bind to specific isoforms of the human retinoic acid receptor- gamma (RAR- gamma ). In addition, several monoclonal antibodies are described which bind to human RAR- gamma , but not to mouse or which bind to RAR- gamma 1, but not to RAR- gamma 2. Methods and kits are described which allow one to detect the isotype of RAR- gamma which is expressed in a test sample. Such methods are useful in determining the tissue specific pattern of expression of various RAR- gamma isoforms.